| Дата | Событие | Место |
| 04 Dec | MTE Muay Thai Extremo | Sassaki Events, Ponta Grossa, Parana, Brazil | |
| 04 Dec | Stockport MMA The Carnage Continues | Chapel Leisure Centre, England | |
| 04 Dec | ECF 33 Holiday Havoc | The Space, Westbury, New York, United States | |
| 04 Dec | UFC Fight Night Dec. 4 | UFC Apex, Las Vegas, Nevada, United States | |
| 04 Dec | Impact Promotions Beatdown at the Beach 22: Pro-Am 2 | Laketown Wharf, Panama City Beach, Florida, United States | |
| 04 Dec | DCS 76 Seasons Beatings 2021 | Pinnacle Bank Arena, Lincoln, Nebraska, United States | |
| 04 Dec | CC 5 Cage Conflict 5: Resistance | The Devenish, Belfast, Northern Ireland | |
| 04 Dec | Fight Club Den Haag Akira FC 4 | Boksschool Houwaart, Den Haag, Zuid-Holland, The Netherlands | |
| 04 Dec | Arena Global Arena Global 15 | Rio de Janeiro, Rio de Janeiro, Brazil, Brazil | |
| 04 Dec | EFC 91 EFC Worldwide 91 | EFC Performance Institute, Johannesburg, South Africa | |
| 04 Dec | B2 Fighting Series 142 Kentucky | Central Bank Center, Lexington, Kentucky, United States | |
| 04 Dec | OFU 1 OFU Entertainment | Balmoral Convention Center, Lagos, Nigeria | |
| 04 Dec | EMC 8 Elite MMA Championship 8 | Areal Bohler, Dusseldorf, Germany | |
| 04 Dec | Caged Steel 27 Caged Steel Fighting Championship 27 | Doncaster Dome, Doncaster, England | |
| 04 Dec | Shamrock FC Shamrock 334 | Ameristar Casino, St. Charles, Missouri, United States | |
| 04 Dec | FNC Armagedon Finals | Dvorana Gradski Vrt, Osijek, Croatia | |
| 04 Dec | AOW 21 Art of War Cage Fighting 21: The Rumble at Rivers | Rivers Casino, Philadelphia, Pennsylvania, United States | |
| 04 Dec | SFC Shark Fight Championship 5 | Ginassyoum Poliesportivo Dayson Siqueira Pinto, Rio Preta da Eva, Amazonas, Brazil | |
| 04 Dec | NFC National Fighting Championship: Xmas Party | District Atlanta, Atlanta, Georgia, United States | |
| 04 Dec | Oktagon MMA Ostrava 2021 | Ostravar Arena, Ostrava, Czech Republic | |
| 04 Dec | UCC 50 Ultimate Combat Challenge | Los Andes Mall, San Miguelito, Panama | |
| 04 Dec | SFC 3 San Francisco Combat 3 | Napa Valley Expo, Napa, California, United States | |
| 04 Dec | SEC Southeastern Elite Combat | Crestview Community Center, Crestview, Florida, United States | |
| 05 Dec | MPL 2 Muradov Professional League 2 | Sports College of Andijan, Andijan, Uzbekistan | |
| 05 Dec | Clan Wars VIP Fight Night | Crowne Plaza Hotel, Shaw's Bridge, Belfast, Northern Ireland | |
| 05 Dec | RMMA 1 Rogue MMA 1 | Melbourne Pavilion, Kensington, Victoria, Australia | |
| 05 Dec | KOTC Kick Start | Toyota Arena, Ontario, California, United States | |
| 09 Dec | WCC 003 Mendez vs. de Castro | Arena Bar, Barranco, Lima, Peru. | |
| 10 Dec | OFC 129 Omaha Fight Club: It's Fight Night | Omaha Design Center, Omaha, Nebraska, United States | |
| 10 Dec | Flex Fight Series Beast Mode Vol. 8 | The Sports Arena, St. James, New York, United States | |